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Carney triad
Carney triad is a synchronous or metachronous association of gastric gastrointestinal stromal tumors (GIST), pulmonary chondroma and extra-adrenal paraganglioma
Prevalence
Unknown
Age of Onset
ICD-10
D44.8
Inheritance
This condition does not appear to have a clear pattern of inheritance.
Rare View
A rare non-hereditary condition characterized by gastrointestinal stromal tumors (GISTs, intramural mesenchymal tumors of the gastrointestinal tract), pulmonary chondromas and extraadrenal paragangliomas. Most patients initially present with two of the three tumors. SDHD, SDHB or SDHC germline mutations are a likey cause. Life-long follow-up should be offered to all patients with the Carney triad.
5 Facts you should know
FACT
Consists of three tumor types: gastric gastrointestinal stromal tumor, pulmonary chondroma, and extra-adrenal paraganglioma
FACT
Most patients initially present with two of the three tumors
FACT
The main symptoms at presentation are gastrointestinal bleeding, epigastric pain, anemia and palpable abdominal mass
FACT
GIST occurs in 99% of cases
FACT
GIST associated with Carney's triad are mostly indolent
Interest over time
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Common signs & symptoms
Abdominal pain
Pain in stomach
Diarrhea
Watery stool
Fatigue
Nausea and vomiting
Gastrointestinal hemorrhage
Gastrointestinal bleeding
Gastrointestinal stroma tumor
Leiomyosarcoma
Pheochromocytoma
Top Clinical Trials
At the time this analysis was conducted, there were no interventional clinical studies being conducted.
Top Treatments in Research
At the time this analysis was conducted, there were no treatments in development for this disease.