Rare Endocrinology News
Disease Profile
Cerebral palsy
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
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Age of onset
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ICD-10
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Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Mixed cerebral palsy
Categories
Nervous System Diseases
Summary
Cerebral palsy refers to a group of neurological disorders that can affect the brain and/or spinal cord. Signs and symptoms generally appear during infancy or early childhood and vary based on the type of cerebral palsy (spastic cerebral palsy, dyskinetic cerebral palsy, ataxic cerebral palsy, and mixed cerebral palsy), the severity of the condition and which area(s) of the brain are affected. Common features include a lack of muscle coordination when performing voluntary movements (
Treatment
FDA-Approved Treatments
The medication(s) listed below have been approved by the Food and Drug Administration (FDA) as orphan products for treatment of this condition. Learn more orphan products.
- AbobotulinumtoxinA(Brand name: Dysport) Manufactured by Ipsen Limited
FDA-approved indication: Treatment of lower limbspasticity in pediatric patients 2 years of age and older.
National Library of Medicine Drug Information Portal
Medline Plus Health Information
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
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Cerebral Palsy Foundation
3 Columbus Circle
15th Floor
New York, NY 10019
Telephone: 212-520-1686
E-mail: info@yourcpf.org
Website: https://yourcpf.org/ -
Child Neurology Foundation
201 Chicago Avenue #200
Minneapolis, MN 55415
Telephone: 952-846-7942
Website: https://www.childneurologyfoundation.org -
Pedal with Pete [For Research on Cerebral Palsy]
P.O. Box 1233
Worthington, OH 43085
Telephone: +1-614-527-0202
E-mail: pwp@pedal-with-pete.org
Website: https://pedal-with-pete.org/ -
Reaching for the Stars, Inc (RFTS, Inc)
3000 Old Alabama Road
Suite 119 – 300
Alpharetta, GA 30022
Toll-free: (855) 240-RFTS (7387)
E-mail: info@reachingforthestars.org
Website: https://reachingforthestars.org/ -
United Cerebral Palsy (UCP)
1825 K Street, NW
Suite 600
Washington, DC 20006
Toll-free: 1-800-USA-5UCP (872-5827)
Telephone: +1-202-776-0406
Fax: +1-202-776-0414
E-mail: info@ucp.org
Website: https://www.ucp.org/
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
- Mayo Clinic has an information page on Cerebral palsy.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
In-Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Cerebral palsy. Click on the link to view a sample search on this topic.
References
- Cerebral Palsy. Centers for Disease Control and Prevention. July 2015; https://www.cdc.gov/ncbddd/cp/index.html.
- Cerebral Palsy. MedlinePlus. August 2013; https://www.nlm.nih.gov/medlineplus/ency/article/000716.htm.
- NINDS Cerebral Palsy Information Page. National Institute of Neurological Disorders and Stroke. July 2015; https://www.ninds.nih.gov/disorders/cerebral_palsy/cerebral_palsy.htm.